{"id":8875,"date":"2024-09-12T05:24:50","date_gmt":"2024-09-12T05:24:50","guid":{"rendered":"https:\/\/www.kauveryhospital.com\/ima-journal\/?p=8875"},"modified":"2025-04-09T10:25:41","modified_gmt":"2025-04-09T10:25:41","slug":"anaesthesia-for-airway-procedures-without-intubation-a-tubeless-ventilation-using-thrive-a-case-report","status":"publish","type":"post","link":"https:\/\/www.kauveryhospital.com\/ima-journal\/ima-journal-september-2024\/anaesthesia-for-airway-procedures-without-intubation-a-tubeless-ventilation-using-thrive-a-case-report\/","title":{"rendered":"ANAESTHESIA FOR AIRWAY PROCEDURES \u2013 WITHOUT INTUBATION   &#8211; A TUBELESS VENTILATION USING THRIVE &#8211; A CASE REPORT"},"content":{"rendered":"<p class=\"caps\">[vc_row][vc_column][vc_column_text]<\/p>\n<p style=\"text-align: justify;\">65-year-old male k\/c\/o carcinoma vocal cord which was diagnosed 10 months back for which he received radiotherapy and underwent microlaryngeal excision of laryngeal papilloma. Then he had h\/o voice change for last 2 months and PET CT revealed SUBGLOTTIC GROWTH for which he was posted for Direct Laryngoscopy + biopsy.<\/p>\n<h2><strong><b>PREOPERATIVE PLANNING:<\/b><\/strong><\/h2>\n<ul>\n<li>Routine investigations were done and blood investigations were found to be within normal limits. ECG- NSR; ECHO- N LV.<\/li>\n<li>After discussion with surgeon, plan of anaesthesia and risk associated with anaesthesia and procedure were clearly explained to patient and attender with written consent.<\/li>\n<li>NPO guidelines were followed.<\/li>\n<li>Pre-medication \u2013 INJ PANTOPRAZOLE 40 MG IV INJ PALANOSETRON 0.075 MG were given.<\/li>\n<\/ul>\n<h2><strong><b>INTRAOPERATIVE MANAGEMENT:<\/b><\/strong><\/h2>\n<ul>\n<li>Patient was positioned supine and ASA Standard monitors were attached and nasal cannula of THRIVE was placed.<\/li>\n<li>Preoperative saturation \u2013 98% under room air.<\/li>\n<li>Preoxygenation was started with 100% oxygen at a rate of 20 l\/min for 3 minutes.<\/li>\n<li>Intravenous anaesthesia was started with Inj midazolam 1 mg; Inj fentanyl 100mcg; Inj propofol 80 mg.<\/li>\n<li>Oxygen flow rate of THRIVE was increased to 50-60 l\/min, once the patient lost consciousness and jaw thrust was used to maintain airway patency until insertion of surgical laryngoscope.<\/li>\n<li>After establishing adequate bag and mask ventilation, INJ atracurium 15mg was given.<\/li>\n<li>Anaesthesia was maintained with TIVA using propofol in titrated doses.<\/li>\n<li>Oxygen saturation was maintained for 15 minutes, then patient had desaturation {spo2 &lt;90% }, bag and mask ventilation was done intermittently to achieve oxygenation once during the 45 mins \u00a0duration of procedure.<\/li>\n<li>Specified THRIVE equipment delivered high flow nasal oxygen varied from 10-60 l\/min with an FI02 of 1 throughout the procedure.<\/li>\n<li>Neuromuscular blockade was reversed with neostigmine.<\/li>\n<li>Jaw thrust with bag-mask ventilation was commenced until return of spontaneous respiration.<\/li>\n<li>The patient was shifted to the recovery room, maintaining his own airway \u00a0\u00a0and got discharged on the same day.<\/li>\n<\/ul>\n<h2><strong><b>DISCUSSION:<\/b><\/strong><\/h2>\n<ul>\n<li>As sharing an airway between the surgeon and the anaesthesiologist is a difficult and challenging task, <em><i>apnoeic oxygenation <\/i><\/em>technique is a reliable method of maintaining oxygenation during short upper airway procedures.<\/li>\n<li>Upper airway surgeries can be performed under endotracheal tube or tubeless technique such as jet ventilation, intermittent apnoeic ventilation and THRIVE.<\/li>\n<\/ul>\n<h2><strong><b>THRIVE &#8211; TRANSNASAL HUMIDIFIED RAPID INSUFFLATION VENTILATORY EXCHANGE:<\/b><\/strong><\/h2>\n<ul>\n<li>A novel technique which utilizes high flow [60-70l\/min] 100%oxygen, which is humidified, warmed to 37 degree C and administered via nasal cannula.<\/li>\n<li>Follows a physiological phenomenon of Aventilatory mass flow \u00a0for providing apnoeic oxygenation<strong><em><b><i>\u00a0<\/i><\/b><\/em><\/strong><\/li>\n<\/ul>\n<h2><strong><b><img loading=\"lazy\" decoding=\"async\" class=\"size-full wp-image-8882 alignnone\" src=\"https:\/\/www.kauveryhospital.com\/ima-journal\/wp-content\/uploads\/2024\/09\/img-3-1-1.jpg\" alt=\"\" width=\"697\" height=\"461\" srcset=\"https:\/\/www.kauveryhospital.com\/ima-journal\/wp-content\/uploads\/2024\/09\/img-3-1-1.jpg 697w, https:\/\/www.kauveryhospital.com\/ima-journal\/wp-content\/uploads\/2024\/09\/img-3-1-1-300x198.jpg 300w\" sizes=\"auto, (max-width: 697px) 100vw, 697px\" \/><\/b><\/strong><\/h2>\n<h2><strong><b>PHYSIOLOGICAL BENEFITS<\/b><\/strong><strong><em><b><i>\u00a0<\/i><\/b><\/em><\/strong><\/h2>\n<ul>\n<li><b><i><\/i><\/b><strong><em><b><i>INCREASE IN APNOEIC TIME AND CARBON DIOXIDE CLEARANCE :<\/i><\/b><\/em><\/strong><\/li>\n<\/ul>\n<p>THRIVE via HFNC has extended the apnoeic window by up to 65 minutes, while reducing the rise in rate of CO2.<\/p>\n<ul>\n<li><b><i><\/i><\/b><strong><em><b><i>GAS CONDITIONING -HEATING AND HUMIDIFICATION:<\/i><\/b><\/em><\/strong><\/li>\n<\/ul>\n<p>By warming and humidifying the gas, high flow reduce the metabolic rate of respiration. Humidification prevent drying of secretions and thus reduce mucus plugging, atelectasis and hypoxia.<\/p>\n<ul>\n<li><b><i><\/i><\/b><strong><em><b><i>FIXED FI02 DELIVERY AND DEAD SPACE WASHOUT:<\/i><\/b><\/em><\/strong><\/li>\n<\/ul>\n<p>It implies minimal room air entrainment.<\/p>\n<ul>\n<li><b><i><\/i><\/b><strong><em><b><i>POSITIVE AIRWAY PRESSURE<\/i><\/b><\/em><\/strong><\/li>\n<\/ul>\n<p>HFNO supplies positive airway pressure of approximately 1cmH2O per 10l\/min flow rate.<\/p>\n<h2><b><\/b><strong><b>BENEFITS IN ANAESTHESIA PRACTICE <\/b><\/strong><\/h2>\n<ul>\n<li><b><i><\/i><\/b><strong><em><b><i>DIFFICULT AIRWAY MANAGEMENT<\/i><\/b><\/em><\/strong><\/li>\n<\/ul>\n<p>This technique affords the <em><i>luxury of time<\/i><\/em>\u00a0to think and utilize the other method of securing the airway while <em><i>maintaining oxygenation <\/i><\/em>and reduces the morbidity. One should be aware that this is not applicable in complete upper airway obstruction.<\/p>\n<ul>\n<li><b><i><\/i><\/b><strong><em><b><i>AIRWAY MANAGEMENT IN OBESE AND PREGNANT PATIENTS<\/i><\/b><\/em><\/strong><\/li>\n<\/ul>\n<p>Both have risk for aspiration and desaturation, this technique is used for preoxygenation to decrease the apnoeic period. \u00a0Used as an adjuvant to assist alveolar recruitment post extubation.<\/p>\n<ul>\n<li><b><i><\/i><\/b><strong><em><b><i>TUBELESS FIELD SURGERY<\/i><\/b><\/em><\/strong><\/li>\n<\/ul>\n<p>To provide an <em><i>unobscured surgical field<\/i><\/em> while maintaining oxygenation and anaesthesia during airway procedures \u00a0including upper airway and larynx \u00a0such as vocal cord biopsy, balloon dilatation, subglottic stenosis, bronchoscopy, endoscopy.<\/p>\n<ul>\n<li>In this technique patient can be spontaneously breathing or apnoeic with full muscle relaxation, while anaesthesia is maintained with TIVA.<\/li>\n<li>It prolongs the safe apnoea time and has low risk for barotrauma. Prevents ETT related injury, avoids vocal cord movement and interruptions of intermittent intubation.<\/li>\n<\/ul>\n<ul>\n<li><b><i><\/i><\/b><strong><em><b><i>RESPIRATORY SUPPORT DURING PROCEDURAL SEDATION <\/i><\/b><\/em><\/strong><\/li>\n<\/ul>\n<p>Used in conscious sedation procedures such as bronchoscopy , colonoscopy, gastroscopy \u00a0where supplemental oxygen is required.<\/p>\n<h2><strong><b><img loading=\"lazy\" decoding=\"async\" class=\"size-full wp-image-8881 alignnone\" src=\"https:\/\/www.kauveryhospital.com\/ima-journal\/wp-content\/uploads\/2024\/09\/img-3-2-1.jpg\" alt=\"\" width=\"671\" height=\"474\" srcset=\"https:\/\/www.kauveryhospital.com\/ima-journal\/wp-content\/uploads\/2024\/09\/img-3-2-1.jpg 671w, https:\/\/www.kauveryhospital.com\/ima-journal\/wp-content\/uploads\/2024\/09\/img-3-2-1-300x212.jpg 300w\" sizes=\"auto, (max-width: 671px) 100vw, 671px\" \/><\/b><\/strong><\/h2>\n<h2><strong><b>LIMITATIONS:<\/b><\/strong><\/h2>\n<p>Hypercapnia is a valid concern as monitoring of end tidal co2 throughout the procedure is difficult.<\/p>\n<h2><strong><b>CONCLUSION:<\/b><\/strong><\/h2>\n<p style=\"text-align: justify;\">THRIVE has improved our practice and patient safety in difficult airway. Combination of THRIVE with TIVA offers a good alternative to conventional anaesthesia with microlaryngeal tubes and jet ventilation in short airway procedures.<\/p>\n<h2><strong>REFERENCES:<\/strong><\/h2>\n<ul>\n<li>1 May 2018 | Reza Nouraei, James Richard Shorthouse, James Keegan, Fran Haigh, Kate Heathcote, Anil Patel, Michael Girgis | ENT, Head and Neck, Laryngology \/ Swallowing \/ Voice<\/li>\n<li>Bharathi MB, Kumar MRA, Prakash BG, Shetty S, Sivapuram K, Madhan S. New Visionary in Upper Airway Surgeries-THRIVE, a Tubeless Ventilation. Indian J Otolaryngol Head Neck Surg. 2021 Jun;73(2):246-251. doi: 10.1007\/s12070-021-02491-2. Epub 2021 Mar 30. PMID: 34150599; PMCID: PMC8163920.<\/li>\n<\/ul>\n<p>&nbsp;<\/p>\n<p><strong><img loading=\"lazy\" decoding=\"async\" class=\"alignleft wp-image-3069 size-thumbnail\" src=\"https:\/\/www.kauveryhospital.com\/ima-journal\/wp-content\/uploads\/2021\/08\/Dr-Velumurgan-150x150.jpg\" alt=\"\" width=\"150\" height=\"150\" srcset=\"https:\/\/www.kauveryhospital.com\/ima-journal\/wp-content\/uploads\/2021\/08\/Dr-Velumurgan-150x150.jpg 150w, https:\/\/www.kauveryhospital.com\/ima-journal\/wp-content\/uploads\/2021\/08\/Dr-Velumurgan-300x300.jpg 300w, https:\/\/www.kauveryhospital.com\/ima-journal\/wp-content\/uploads\/2021\/08\/Dr-Velumurgan.jpg 360w\" sizes=\"auto, (max-width: 150px) 100vw, 150px\" \/>Dr Velmurugan Desingh<\/strong><br \/>\n<em>Head of the Department,<\/em><br \/>\n<em>Department of Anaesthesiology<\/em><br \/>\nKauvery Hospital, Chennai<\/p>\n<p>&nbsp;<\/p>\n<p>&nbsp;<\/p>\n<p><strong><img loading=\"lazy\" decoding=\"async\" class=\"alignleft wp-image-7520 size-thumbnail\" src=\"https:\/\/www.kauveryhospital.com\/ima-journal\/wp-content\/uploads\/2023\/10\/dr.dhiveya-150x150.jpg\" alt=\"\" width=\"150\" height=\"150\" \/>Dr S. Dhiveya<\/strong><br \/>\n<em>Second Year DNB Resident,<\/em><br \/>\n<em>Department of Anesthesiology,<\/em><br \/>\nKauvery Hospital, Chennai[\/vc_column_text][\/vc_column][\/vc_row]<\/p>\n","protected":false},"excerpt":{"rendered":"<p>[vc_row][vc_column][vc_column_text] 65-year-old male k\/c\/o carcinoma vocal cord which was diagnosed 10 months back for which he received radiotherapy and underwent microlaryngeal excision of laryngeal papilloma. Then he had h\/o voice<\/p>\n","protected":false},"author":2,"featured_media":8876,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[79],"tags":[],"class_list":["post-8875","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-ima-journal-september-2024"],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v24.0 - https:\/\/yoast.com\/wordpress\/plugins\/seo\/ -->\n<title>ANAESTHESIA FOR AIRWAY PROCEDURES \u2013 WITHOUT INTUBATION  - A TUBELESS VENTILATION USING THRIVE - A CASE REPORT<\/title>\n<meta name=\"description\" content=\"5-year-old male k\/c\/o carcinoma vocal cord which was diagnosed 10 months back for which he received radiotherapy and underwent microlaryngeal excision of laryngeal papilloma.\" \/>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" 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