End Stage Renal Failure [eGFR < 15%] – means kidneys don’t work-requiring renal replacement therapy in the form of Dialysis or Renal Transplantation.

End Stage Renal Failure – Is not fatal. Good quality treatments are available in the form of dialysis or renal transplantation.

Renal transplant – best option for an individual

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  • Any blood related donor is acceptable for transplantation provided relationship is established by genetic methods.
  • Same blood group renal transplantation means receiving kidney from either same blood group or from O positive blood group
  • Deceased donor-those who are brain dead in the intensive care unit following a road traffic accident or stroke
  • Statistics suggests that about 150000 people in India are waiting for renal transplantation
  • Only 1 out of 30 people who need a kidney receives one
  • 90% of the patients in the waiting list die without getting the kidney
  • Availability of kidneys for transplantation from deceased donor (Cadaver’s) – always a shortage due to denial of familial consent, demand supply mismatch, lack of awareness in various sub urban hospitals, economic constraints for transplantation
  • Interesting to note that countries like Spain have made organ donation compulsory after death!!

Newer Milestone in Transplantation

ABO Incompatible renal transplantation

  • Don’t need same blood groups for transplant-Across the blood group-Cross the barrier.
  • Patient needs to remove antibodies in them before they acquire the kidney from donor.
  • Excellent outcomes as same blood group transplantation with no major adverse effects.

Paired Kidney Exchange Program

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Dr. B.Balaji Kirushnan

Article by Dr. B.Balaji Kirushnan,
MBBS, MD (General Medicine), PGDHSC Diabetology, DNB (Nephrology)
Associate Consultant Nephrology,
Kauvery Hospital