What are Brain lesions?

Brain lesions

A brain lesion is a damaged or destructed area of the brain. It may occur due to head trauma or other diseases that can cause inflammation, malfunction, or destruction of brain cells or brain tissue. The lesion might be localised to one part of the brain or they may be widespread.

What are the symptoms of Brain lesions?

Headaches 1
Headaches
Neck pain 1
Neck pain or stiffness
Visual disturbances
Nausea, vomiting and lack of appetite
Loss of consciousness
Vision changes or eye pain
Changes in personality
Changes in personality
Trouble concentrating
Trouble concentrating
memory loss
Memory loss
Seizures 3
Seizures
Fever 3
Fever
Difficulty in moving
Difficulty in moving
Delayed speech blurred vision
Delayed speech, blurred vision, impaired hearing
Language and speech problems
Language and speech problems
  • Traumatic – gunshot wound
  • Infectious – meningitis
  • Malignant – glioma
  • Benign brain lesions – meningioma – stroke
  • Vascular – neurofibromatosis
  • Genetic – multiple sclerosis
  • Immune – multiple sclerosis
  • Plaques (deposits of substances in brain tissue) – Alzheimer’s disease
  • Brain cell death or malfunction – Parkinson’s disease
  • Ionizing radiation – radiation leading to death of healthy brain tissue

Generalised Seizures

  • Absence seizures
  • Tonic seizures
  • Atonic seizures
  • Clonic seizures
  • Myoclonic seizures
  • Tonic – clonic seizures
  • Aging
  • Vascular conditions such as stroke, high blood pressure and cerebral artery aneurysms
  • Family history of brain lesions
  • Trauma to the brain
  • Poor diet, consumption of food with high fat and cholesterol content
  • Infections, harmful germs or bacteria in the brain
  • Primary tumors or metastatic tumors
  • Toxins in the body such as excessive amounts of alcohol or cigarette smoke, elevated amounts of ammonia and urea due to kidney issues
  • Autoimmune diseases such as lupus and multiple sclerosis.
  • Plaques or build-up of abnormal protein in the brain tissues
  • Exposure to radiation or certain chemicals that increase the risk of tumors and lesions

Physical and neurological examination along with complete history of the patient is required to diagnose brain lesion. Most of the cases will also require diagnostic tests.

Diagnostic tests:

  • CT scan
  • MRI
  • Angiography
  • Lumbar puncture
  • Blood tests

Treatment and prognosis of brain lesions depend upon the type of lesion, its location, and the cause.

Common approaches

  • Surgery to remove the lesions that are caused by a brain tumor
  • Chemotherapy and radiation therapy for cancerous lesions
  • Medication for infections, such as antibiotics or other antimicrobial drugs
  • Medication to change the immune system’s response